Multiple Choice Questions (MCQs)

                                                        

Genome Sequencing Projects

1.  India has sequenced a part of chromosome 11; the other country sharing this chromosome was………..

(a) China                    (b) France

(c) Taiwan                 (d) Japan

Ans. B

2. `Indian Initiative for Rice Genome Sequencing` (HRGS) as a part of international consortium for sequencing of the rice genome was launched by the Department of Biotechnology (DBT), New Delhi, in:

(a) 2001                      (b) 2000

(c) 1998                       (d) 1999

Ans. B

3. Which is the pathogenic strain of E.coli whose genome has been sequenced in 2001?

(a) O157:H7               (b) El T

(c) K-12                      (d) MG1655

Ans. A

4. Whole genome of the first free-living organism was sequenced at:

(a) The institute for Genomic Research (TIGR)

(b) Bayer College of Medicine Human Genome Sequencing Center

(c) The Washington University Genome Sequencing Center

(d) University of Wisconsin-Madison

Ans. A

5. In rice genome sequencing project, the maximum number of chromosomes has been sequenced by:

(a) China                    (b) France

(c) USA                       (d) Japan

Ans. D

6. Whole genome of the first free-living organism was sequenced in:

(a) 1998                      (b) 1995

(c) 1985                       (d) 1977

Ans. B

7. Among the diploid crops, the ………. Possesses the smallest genome.

(a) Potato                   (b) Tomato

(c) Oat                        (d) Eggplant

Ans. B

 

8. Among prokaryotes, the smallest genome is of:

(a) Bacillus subtilis    

(b) Haemopholus influenza KW20

(c) Salibacter (Acidobacteri(a)usitatus Ellin6076

(d) Carsonella ruddii PV

Ans. D

9. The International Rice Genome Sequencing Project (IRGSP) was initiated by……..:

(a) UK                        (b) India

(c) USA                       (d) Japan

Ans. D

10. The genome of Haemophilus influenza is small and consists of ……….. genes in the entire genome:

(a) 1840 genes           (b) 1740 genes          

(c) 1640 genes           (d) 1540 genes

Ans. B

11. The genome of Neurospora crussa is organized in ………….. Chromosomes:

(a) 9                            (b) 8

(c) 7                             (d) 6

Ans. C

12. 12. The maximum number of genome sequencing projects has been carried out at:

(a) Germany              (b) Canada

(c) UK                         (d) USA

Ans. D

 13. Rattus norvegicus is commonly known as the:

(a) Norwegian rat     (b) Common rat

(c) Brown rat             (d) All of these

Ans. D

14. This international Human Genome Project started in:

(a) December, 1990  (b) October, 1990

(c) August, 1990       (d) June, 1990

Ans. B

15. Genomes of human and mice had been sequenced; both had revealed similarity in about ……….. genes.

(a) 3000                      (b) 1500

(c) 300                         (d) 150

Ans. C

16. The Institute for Genomic Research (TIGR) is situated at:

(a) Houston               (b) Berkeley

(c) Wisconsin            (d) Rockville

Ans. D

17. Human Genome Project was completed in 2003; the chromosome no. was sequenced in:

(a) 2006                      (b) 2003

(c) 2000                       (d) 1997

Ans. A

18. Initial sequencing of the human genome was published in 2001 in:

(a) Science                 (b) Nature

(c) Both                      (d) None

Ans. C

19. The progress of HGP was greatly increased after the involvement of a private company … by J.Craig Venter.

(a) Syngenta  (b) Strand Genomics

(c) Celera Genomics

(d) The Institute for Genomic Research   

Ans. C

20. Which among the following is the largest genome sequenced until now?

(a) Oryza sativa         

(b) Homo sapiens

(c) Caenorhabdtitis elegans

(d) Guillardia theta  

Ans. B

21. Ethernet was described in thesis of …….. submitted to Harvard University.

(a) P.H.O` Farrell     (b) Ray Tomlinson

(c) Robert Metcalfe   (d) Paul Berg

Ans. C

22. Transmission Control Protocol (TCP) was developed by:

(a) Tom Trustcott, Jim Ellis and Steve Bellovin

(b) Allan Maxam, Walter Gilbert and Frederick Sanger

(c) Vint Cerf and Robert Khan

(d) Bill Gates and Paul Allen

Ans. C

23. The aspects of bioinformatics that are applied to drug discovery and drug designing are known as:

(a) Medical informatics      

(b) Biomedical informatics

(c) Pharmacoinfomratics

(d) All of the above

Ans. D

24. Bioinformatics is a multidisciplinary subject and requires the knowledge of many subjects. Pick the odd one out from the following:

(a) Mathematics                  (b) Geography

(c) Information technology (d) Biology  

Ans. B

25. Bioinformatics is:

(a) Searching and retrieval of data

(b) The storage, annotation and analysis of data

(c) A newly emerged inter-disciplinary scientific discipline that interfaces the developments of computer science and information technology with biological sciences

(d) All of these

Ans. D

 

26. The application of genomic approaches and technologies to the identification of drug targets is known as:

(a) Pharmacology    

(b) Pharmacogenetics

(c) Pharmacogenomics

(d) Pharmacoinformatics

Ans. D

27. The SWISS- PROT database was created by:

(a) European Molecular Biology Laboratory (EMBL)

(b) Department of Medical Biochemistry, University of Geneva

(c) None of the above

(d) Both of these

Ans. D

28. The Compact Disk (CD) was launched in:

(a) 1984                      (b) 1983         

(c) 1982                       (d) 1981

Ans. B

29. Which of the following is used for structure visualization?

(a) MODELLER        (b) CLUSTAL

(c) BLAST                  (d) Cn3D

Ans. D

30. A drug can act as a:

(a) Poison                  (b) Medicine

(c) Both (a) & (b)       (d) None of these

Ans. C

31. A ligand is:

(a) A molecular group        

(b) A molecule

(c) An ion

(d) All of these

Ans. D

32. Which serves as a drug?

(a) Inorganic substances

(b) Products from animal sources

(c) Plant extracts

(d) All of the above

Ans. D

33. Altered drug behavior is studied in:

(a) Molecular Biology (b) Genetics

(c) Pharmacogenetics   (d) Biochemistry

Ans. C

34. Which act as a drug target?

(a) Nuclear Receptors (b) Enzymes

(c) Ion Channels       (d) All of these         

Ans. D

35. The EBCDIC contains ……. Bit in its zone.

(a)  8               (b)  6

(c)  4                (d)  2

Ans. C

36. A computer consists of:

(a) Input and Output Devices (I/O devices)

(b) Memory and Secondary Storage

(c) Central Processing Unit (CPU)

(d) All of these

Ans. D

37. The hexadecimal value 1E is equal to the octal value ………

(a) 36              (b) 34

(c) 32               (d) 30

Ans. D

38. The first microprocessor was:

(a) 8080                      (b) 8008

(c) 4040                       (d) 4004

Ans. D

39. 1 GB is equal to ………… bytes.

(a) 1,099,511,628,000

(b) 1,073,741,824

(c) 1,048,576

(d) 1,024

Ans. B

40. The basic functions of processor are:

(a) Executing arithmetic and logical operations

(b) Controlling each operation

(c) Interfacing with main memory

(d) All of these

Ans. D

41. The decimal value 30 will be ………… in binary number system.

(a) 10111                    (b) 11011

(c) 11101                     (d) 11110

Ans. D

42. The full form of CPU is:

(a) Computer`s Personal Unit

(b) Computer`s Processing Unit

(c) Central Processing Unit

(d) Central Primary Unit

Ans. C

43. Microsoft Word (MS word) made its first appearance in:

(a) 1984                      (b) 1983

(c) 1982                       (d) 1981

Ans. B

44. System board is also called as:

(a) Peripheral board (b) Hard board

(c) Peripheral Component Board

(d) Mother board

Ans. D

45. UNIX was developed by:

(a) Kenneth Thompson and Dennis Ritchie

(b) Tom Truscott, Jim Ellis and Steve Bellovin

(c) Vint Cerf and Robert Khan

(d) Bill Gates and Paul Allen

Ans. A

46. Which among these is not a kind of memory?

(a) Peripheral            (b) Cache

(c) Virtual                  (d) RAM

Ans. A

47. Vacuum tubes were used in:

(a) Fourth generation computer

(b) Third generation computer

(c) Second generation computer

(d) First generation computer

Ans. D

48. Which among the following is an input device?

(a) Speaker                (b) Printer

(c) Touch pad            (d) Monitor

Ans. B

49. John Von Neumann invented:

(a) UNIVAC              (b) EDVAC

(c) ENIAC                  (d) ABC

Ans. B

50. Which among the following is an output device?

(a) Scanner                (b) Monitor

(c) Mouse                  (d) Keyboard

Ans. B